CYCLICAL CONNECTION BETWEEN TRANSGENERATIONAL TRAUMA, HOSTILE ENVIRONMENT, EPIGENETIC MECHANISMS AND CORTISOL HORMONE

This narrative review demonstrates the close connection between impact of traumas experienced across generations, added to an environment unpredictability during organism’s life history. The effects trauma can be passed on subsequent generations through epigenetic mechanisms and changes in stress response axis, sensitivity glucocorticoid receptors, cortisol release. When associated, they form a line continuous cause effect history individuals involved their future favoring new environments risks that lead more adverse situations traumas. Consequently, descendants nearby people impacted by cascading related existing difficulties considered hostile or unpredictable.